P‐18 Cryptococcosis in São Paulo (Brazil): clinical and epidemiological features (1992–2003)
Identifieur interne : 008A52 ( Main/Exploration ); précédent : 008A51; suivant : 008A53P‐18 Cryptococcosis in São Paulo (Brazil): clinical and epidemiological features (1992–2003)
Auteurs : S. C. Chiesa [Brésil] ; R. C. Castro [Brésil] ; M. Otsuka [Brésil] ; N. S. Michalany [Brésil] ; C. E. Larsson Jr [Brésil] ; C. E. Larsson [Brésil]Source :
- Veterinary Dermatology [ 0959-4493 ] ; 2004-08.
Abstract
Cryptococcosis is a relatively frequent disease in the southwest region of Brazil. We have diagnosed 19 cases of cryptococcosis (1.6 cases/year) at our hospital in the last 12 years. Cats were most frequently affected (18 feline and one canine) among our cases. The disease was most frequent in purebred Siamese cats (55.5 %), and in male cats (77.8 %) with an age predisposition of 4‐ to 6‐year‐old animals (56.2%) and 7‐ to 9‐year‐old animals (18.8 %). The diagnosis was established by cytologic and histopathologic examination, fungal culture and serologic evaluation. All cases was caused by Cryptococcus neoformans serotype AD. We used fungal culture as the gold standard for the diagnosis. Histopathology was positive in 93.3% of cases and the cytologic examination in 75% of cases. Most cats were FIV and FeLV negative. Ocular involvement was found only in the canine case which is the first report of canine cryptococcosis in Brazil. Itraconazole (10 mg/kg once daily) as the sole therapy or in conjunction with 5‐fluorocytosine was effective in 95% of the patients. Funding: Self‐funded.
Url:
DOI: 10.1111/j.1365-3164.2004.00414_18.x
Affiliations:
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Michalany</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Faculdade de Medicina Veterinária, Universidade de São Paulo, São Paulo, Brazil; Escola Paulista de Medicina, Universidade Federal do Estado de São Paulo, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Larsson Jr, C E" sort="Larsson Jr, C E" uniqKey="Larsson Jr C" first="C. E." last="Larsson Jr">C. E. 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Larsson</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Faculdade de Medicina Veterinária, Universidade de São Paulo, São Paulo, Brazil; Escola Paulista de Medicina, Universidade Federal do Estado de São Paulo, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Veterinary Dermatology</title><title level="j" type="alt">VETERINARY DERMATOLOGY</title><idno type="ISSN">0959-4493</idno><idno type="eISSN">1365-3164</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="page" from="46">46</biblScope><biblScope unit="page" to="46">46</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08">2004-08</date></imprint><idno type="ISSN">0959-4493</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0959-4493</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cryptococcosis is a relatively frequent disease in the southwest region of Brazil. We have diagnosed 19 cases of cryptococcosis (1.6 cases/year) at our hospital in the last 12 years. Cats were most frequently affected (18 feline and one canine) among our cases. The disease was most frequent in purebred Siamese cats (55.5 %), and in male cats (77.8 %) with an age predisposition of 4‐ to 6‐year‐old animals (56.2%) and 7‐ to 9‐year‐old animals (18.8 %). The diagnosis was established by cytologic and histopathologic examination, fungal culture and serologic evaluation. All cases was caused by Cryptococcus neoformans serotype AD. We used fungal culture as the gold standard for the diagnosis. Histopathology was positive in 93.3% of cases and the cytologic examination in 75% of cases. Most cats were FIV and FeLV negative. Ocular involvement was found only in the canine case which is the first report of canine cryptococcosis in Brazil. Itraconazole (10 mg/kg once daily) as the sole therapy or in conjunction with 5‐fluorocytosine was effective in 95% of the patients. 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Michalany</name><name sortKey="Otsuka, M" sort="Otsuka, M" uniqKey="Otsuka M" first="M." last="Otsuka">M. Otsuka</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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